FUNGI
- Organisms that exhibit dimorphism and grow on Sabouraud’s medium (low pH): Fungi
- Type of agar used for most fungi? Sabouraud agar
- Organism that causes athletes foot (tinea pedis) à Trichophyton
- Which fungal infection leads to superficial skin disease? Trichophyton
- Epidermophyton & Microsporum cause dermatophytosis. Tx w/ Griseofulvin
- Which fungus causes cerebral/brain infarct?
- Cryptococcus à may spread into the meninges and cause Cryptococcal Meningitis
- Aspergillus à causes aspergilloma “fungus ball” in the lungs causing pulmonary infection in ppl with AIDS or have undergone organ transplant
- Mucormycosis à Pt’s w/ diabetic ketoacidosis, burns, or leukemia are particularly susceptible. It results in black, dead tissue in the nasal cavity and blocks the blood supply to the brain.
- Mucormycosis is found in blood vessels (endothelium) & is often related to diabetic pts
- Aflatoxin is what produced by what fungus? Aspergillus
- Cell immunity is most important for? Intracellular parasite
- Which one can be seen as an intracellular organism? Histoplasmosis
- In infected tissues, yeast cells of Histoplasmosis are found within macrophages.
- Disseminated fungi? Histoplasmosis
Yeast in macropages, bird-bat drooping, via respiratory droplets different than the rest of them
- Which pathogen causes granulomatous lesion in lung resembling TB, similar symptoms? Histoplasmosis
- What doesn’t give you granulomas? à Gonorrhea
- Histoplasmosis, M tuberculosis and tertiary syphilis are granulomatous (immune system walls off)
- What does not cause a mucosal or epidermal rash? Histoplasmosis
- Avian/bird related fungi à Histoplasma capsulatum
- Most common cause of fungal meningitis? Cryptococcosis
What is dimorphism in fungus? Mycelium (mold) or as yeast
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